CYP1A1 GENE POLYMORPHISM AND NASOPHARYNGEAL CARCINOMA IN ALGERIAN POPULATION
نویسندگان
چکیده
منابع مشابه
Glutathione S-transferase M1 gene polymorphism in Thai nasopharyngeal carcinoma.
Nasopharyngeal carcinoma (NPC) is a serious health problem in Thailand. It is caused by the combined effects of Epstein-Barr virus (EBV), carcinogens and genetic susceptibility. The glutathione S-transferase M1 gene (GSTM1) encodes a phase II enzyme responsible for detoxifying carcinogenic electrophiles. Polymorphic null forms of the gene GSTM1 lack enzyme activity and have been associated with...
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OBJECTIVE To estimate and compare the frequency of CYP1A1*2A gene polymorphisms in a Brazilian population and determine the possible contribution of these genetic variations to lung cancer risk. METHODS The study population included 200 patients with lung cancer, and the control group consisted of 264 blood donors. Genomic DNA was obtained from peripheral blood samples. The PCR-RFLP method wa...
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In order to investigate the piÃ2 gene alterations in nasopharyngeal carcinoma (NPC), we have examined for mutations and deletions of the l>lli gene in samples of NPC including 3 cell lines, 3 xenografts, and 20 primary tumors with matched blood DNA as controls. Using single-strand conformation polymorphism and direct sequencing analysis, no piÃ2 gene mutations were detected in the NPC primary t...
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ژورنال
عنوان ژورنال: Current Trends in Natural Sciences
سال: 2020
ISSN: 2284-953X
DOI: 10.47068/ctns.2020.v9i18.030